
S.E.M.I. – Side Effects May Include
PRICE COMPARISON
DLC & ADD-ONS
1INCLUDED IN
1ABOUT THIS GAME
Up to Four Players Can Escape Together in S.E.M.I.
S.E.M.I. – Side Effects May Include is a cooperative online game where players must escape from a peculiar mental clinic. You and up to three friends tackle this chaotic challenge, facing off against deranged staff and erratic patients. Each experience is different, characterized by unpredictable situations, unpredictable abilities, and demanding gameplay that tests your and your team’s coordination.
Embrace Chaos with Unpredictable Powers
The game's hallmark is its mix of randomized abilities stemming from ingesting in-game pills. Each pill can bestow a wild set of powers—sometimes beneficial, sometimes debilitating. For example, take the “Bipolar force” pill to become an invulnerable monster one moment, then a vulnerable ragdoll the next. This unpredictability adds layers of strategy and hilarity, urging players to adapt and think creatively in each encounter.
Navigate an Obstacle-Laden Environment
Expect to confront a myriad of devious obstacles, puzzles, and deadly traps scattered throughout the clinic. Rooms with shifting gravity, moving walls, and surprise hazards will challenge even the most careful strategists. Communication becomes essential; players must coordinate their efforts to escape, ensuring no one member causes the team to stumble. A single misstep can set off a chain reaction, eliminating the entire squad in seconds.
Interface with Engaging Voice Chat Mechanics
Voice chat is integral to your success in S.E.M.I. Cooperation means strategizing together to overcome increasingly difficult challenges. You can help your friends escape traps and brawl with other patients by employing unique abilities in tandem. This reliance on communication heightens the tension and rewards well-planned teamwork, bringing friends closer in a setting that thrives on chaos.
Customize Your Escape with Style
After each escape attempt, players receive a quirky medical report detailing their “diagnosis” based on their actions. This humorous touch not only ties the gameplay to its narrative but also immerses players in the absurdity of the scenario. Unlock new costumes and decorations upon successful breakthroughs, allowing each subsequent escape to be more stylish than the last, adding a layer of personalization to your adventures.
Randomly Generated Rooms for Replayability
The randomly generated nature of the rooms ensures that no two outings feel the same. Each playthrough offers something fresh, with configurations and puzzles keeping players on their toes. Returning players will find their skills put to the test against a constantly shifting backdrop, creating a challenge that remains engaging over time.
Will You Survive the Mental Hospital?
Ultimately, S.E.M.I. is not just about escaping; it's about surviving the unpredictable madness of teamwork. The question remains: can you and your friends navigate the chaos and evade the pitfalls of the clinic? Prepare for a hilariously intense experience, where camaraderie could either lead to victory or chaotic defeat, all waiting for you on PC.
PRICE HISTORY
Historical Low
£5.59
Steam · 23 Jan 2026
Average Price
£6.79
all stores · 6 months
Lowest Price Now
£7.99
Steam
Historical Low: £5.59 at Steam on 2026-01-23
Average Price: £6.79
Lowest Price Now: £7.99 at Steam
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